What is the Sedation Troetsch?
- You will be given a sublingual (under-the-tongue) tablet known as a Troetsch before your procedure. This Troetsch is designed to help reduce anxiety and discomfort and contains the following medications:
- Medazepam 3 mg – a benzodiazepine used to relieve anxiety and induce mild sedation.
- Ketamine 25 mg – a dissociative anesthetic used in low doses for pain control and relaxation.
- Ondansetron (Zofran) 4 mg – an anti-nausea medication to reduce the risk of vomiting or nausea.
This medication is absorbed under the tongue and begins working within 15–30 minutes.
Potential Benefits
- Reduced anxiety and stress before the procedure
- Enhanced comfort during minor procedures
- Lower need for intravenous sedation
- Decreased risk of nausea with the addition of ondansetron
Possible Side Effects
Common side effects may include:
- Drowsiness or lightheadedness
- Altered perception or mild euphoria
- Dry mouth or slight numbness under the tongue
Less common but possible effects:
- Nausea or vomiting
- Confusion or disorientation
- Allergic reaction (rash, swelling, breathing difficulty)
- Hallucinations or unusual thoughts (rare at low doses of ketamine)
- Please inform your healthcare provider if you have a history of sensitivity to any of the above medications.
Warnings and Precautions
- Do not drive, operate machinery, or make major decisions for at least 12 hours after taking this medication.
- You must have a responsible adult accompany you home after the procedure.
- Tell your doctor if you are pregnant, breastfeeding, or have liver disease, glaucoma, psychiatric conditions, or a history of substance abuse.
- Inform your provider about all medications you are currently taking, including antidepressants, opioids, and sedatives.